Vertex Pharmaceuticals management check

VRTX · Health Care · Biotechnology · CEO Reshma Kewalramani

Filings as of

86
Management score, ranked 19th of 487Strongest: owner returns. Weakest: dilution. See the best and worst run in Health Care →

6 good · 0 to watch · 0 flagged, across the seven questions below.

  • Good

    Have owners done well?

    Beat its chosen peers

    $100 invested at the start of fiscal 2021 grew to $192, against $125 for the peer group the company picked itself.

  • Good

    Does pay follow performance?

    Pay rose and fell with returns

    Over 5 years, the CEO's pay actually paid (equity valued at the share price) had a correlation of 0.91 with shareholder return. 1 means pay moved in step; below 0, the opposite way.

  • Good

    What does the CEO cost owners?

    0.5% of net income

    $21.1m of reported pay in fiscal 2025, against $4.0bn of net income.

  • n/a

    Do they own the stock?

    No recent CEO filing

    Light activity: no buys, $11.0m sold in six months. 14 of 14 sales ran on pre-arranged 10b5-1 plans.

  • Good

    Are owners being diluted?

    Share count shrinking

    Diluted shares changed -0.5% a year over the last three fiscal years. Stock-based pay was 5.7% of revenue in the latest year.

  • Good

    Is leadership stable?

    7 leadership filings in 3 years

    CEO in the pay table: Reshma Kewalramani. 7 filings under 8-K item 5.02 (officers or directors leaving or joining, or new pay arrangements) in the last 3 years.

  • Good

    Are the books clean?

    No red flags on file

    No restatements, auditor changes or late filings since 2021.

Against the S&P 500

Each check's score (0–100) and how it compares: the share of ranked S&P 500 companies it matches or beats, and the median in Health Care.

CheckScoreAt or aboveSector median
Owner returns100100%26
Pay for performance9585%85
CEO cost7375%44
Skin in the game——46
Dilution5643%68
Stable leadership9069%70
Clean books100100%100

Closest peers

Others in Biotechnology, by management score. Vertex Pharmaceuticals is 2nd of 60 in its sector.

  1. 19VRTXVertex Pharmaceuticals86
  2. 43GILDGilead Sciences82
  3. 93REGNRegeneron Pharmaceuticals77
  4. 136AMGNAmgen73
  5. 199ABBVAbbVie69
  6. 298INCYIncyte61
  7. 401MRNAModerna53
  8. 447BIIBBiogen47

Pay versus performance

From the proxy statement filed April 2, 2026. "Actually paid" values stock awards at the share price, so it rises and falls with the stock.

CEO pay by fiscal yearAs reported Actually paid
$0$22.1m$44.2m20212022202320242025
What $100 becameCompany Peer group
$10020212022202320242025$192
Fiscal yearCEOCEO payActually paidOther executives (avg)$100 becamePeersNet income
2025Reshma Kewalramani$21.1m$38.2m$7.7m$192$125$4.0bn
2024Reshma Kewalramani$21.5m$43.6m$8.1m$170$93−$500.0m
2023Reshma Kewalramani$20.6m$44.2m$7.4m$172$94$3.6bn
2022Reshma Kewalramani$15.9m$29.5m$9.0m$122$90$3.3bn
2021Reshma Kewalramani$15.2m$18.3m$7.2m$93$100$2.3bn

The board says pay is tied most to net product revenue. Its other key measures: Net Product Revenue, Pipeline Progression(1), Adjusted Non-GAAP EBITDA(2).

Insiders and the CEO's stake

Light activity: no buys, $11.0m sold in six months. 14 of 14 sales ran on pre-arranged 10b5-1 plans.

  • SoldCarmen BozicEVP and CMO · 10b5-1 plan$8.0mJun 26, 2026
  • SoldJoy LiuEVP and Chief Legal Officer · 10b5-1 plan$1.2mJul 1, 2026
  • SoldDuncan McKechnieEVP, Chief Commercial Officer · 10b5-1 plan$800kJul 2, 2026
  • SoldOurania TatsisEVP, Chief Reg. & Quality Off. · 10b5-1 plan$787kJul 2, 2026

Leadership and governance on file

Latest shareholder vote results: May 13, 2026, including the say-on-pay vote.

Where the money went

Over 2021–2025: $5.0bn returned to owners in buybacks and dividends, 40% of net income, and $2.9bn of pay in stock.

Fiscal year20212022202320242025
Revenue$7.6bn$8.9bn$9.9bn$11.0bn$12.0bn
Net income$2.3bn$3.3bn$3.6bn−$535.6m$4.0bn
Stock-based pay$441.4m$491.3m$581.2m$698.5m$685.9m
Buybacks$1.4bn$0$427.6m$1.2bn$2.0bn
Dividends—————
Diluted shares260m259m261m258m258m

Educational only, not investment advice. Figures are as filed with the SEC: pay from the proxy's pay-versus-performance table, capital allocation from 10-K XBRL data, insider trades from Form 4s over the last six months, events from the last 5 years of filings. The peer group is the one the company chose. See the method.